Is isopropyl alcohol and microfiber safe for cleaning a glass mousepad?

Yes, isopropyl alcohol (70% or higher) on a microfiber cloth is the safest way to clean hardened polymer residue from a glass mousepad. The polymer coating is what you’re protecting — abrasives, paper towels, or magic erasers will scratch it. Apply alcohol to the cloth, let it sit on residue for 30 seconds, then wipe gently.