Is DDR5 RAM worth it for gaming in Cyberpunk 2077?

No, not really. In Cyberpunk 2077, DDR5-6000 CL30 feels about the same as good DDR4-3600 CL16, with maybe 5-10% gains only if your CPU is maxed out. The game is GPU-heavy, so you’re usually waiting on the graphics card, not the RAM. If you’re building new, get DDR5 since it’s the standard and prices have dropped, but upgrading from a solid DDR4 system just for RAM speed is a waste of money — put that cash toward a better GPU instead.