Can software patches fix missing ECC memory?

No. Software can add checksums or CRC to detect corruption after it happens, but it can’t correct it without hardware redundancy—duplicating memory and checking every read kills performance. Without ECC hardware, memory errors are silent and unrecoverable. For data-critical work, get a board with ECC support like certain Rockchip RK3568 or x86 mini PCs; the RK3588 lacks it and can’t be fixed in software.