Can I visit both the US and Canadian sides of Niagara Falls in one day from Pittsburgh?

A one-day trip from Pittsburgh (~3.5 hours each way) means you pick a side and commit. Hit the American side first — Niagara Falls State Park and the Maid of the Mist boat tour — then cross over for Journey Behind the Falls on the Canadian side if you have time. Queen Victoria Park gives you the full panorama before heading back.