3 Things to Know About the ASUS PRIME B450M-A II M.2 Slot

Only one M.2 slot is available The board has a single M.2 slot (Socket 3, Key M) that supports drives up to 2280 size.

It works with both SATA and PCIe drives The slot accepts SATA and PCIe 3.0 x4 M.2 drives, so you can use either interface.

You must choose between NVMe speed and SATA compatibility With only one slot, you cannot use both a fast NVMe drive and a SATA M.2 drive simultaneously. Pick the type that fits your needs.